Product Usage: This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only.All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food or cosmetic.

Melanotan II_10MG

MT-2

MT-2, also known as Melanotan II, is a synthetic cyclic heptapeptide analog derived from the endogenous melanocortin hormone α-melanocyte-stimulating hormone (α-MSH). It is engineered to interact with melanocortin receptors and is widely utilized in laboratory research focused on melanocortin signaling pathways, receptor binding dynamics, and peptide-mediated cellular communication in controlled experimental models.*

Due to its enhanced receptor affinity and increased stability relative to native α-MSH, MT-2 has been extensively referenced in biochemical, endocrinological, and molecular biology research investigating melanocortin system activity and downstream intracellular signaling mechanisms.*

  • Peptide Name: Melanotan II (MT-2)
  • Peptide Class: Synthetic melanocortin receptor agonist
  • Amino Acid Length: 7 amino acids (cyclic structure)
  • Form: Lyophilized powder
  • Purity: ≥99% (HPLC verified)
  • Quantity: 10 mg per vial
  • Analytical Verification: HPLC and Mass Spectrometry (MS)
  • Manufacturing: Solid-phase peptide synthesis with in-house purification
  • Designation: For Research Use Only (RUO)

$50.00

Products will arrive in a lyophilized (powder) form for maximum stability.

Free domestic shipping on orders over $300

MT-2

Scientific & Research Context

MT-2 has been investigated in published scientific literature as a research compound for studying melanocortin receptor activity, particularly MC1R, MC3R, MC4R, and MC5R, which are involved in diverse biological signaling pathways.* Experimental models have explored MT-2 in the context of pigmentation signaling, energy balance regulation, neuroendocrine communication, and peptide-receptor structure–function relationships.*

In laboratory research settings, MT-2 has been utilized to investigate:*

  • Melanocortin receptor binding and activation mechanisms*
  • α-MSH–derived peptide analog structure–activity relationships*
  • Intracellular signaling cascades associated with melanocortin pathways*
  • Neuropeptide involvement in central and peripheral signaling models*
  • Stability and bioactivity of cyclic peptide analogs*

Its compact cyclic structure, high receptor affinity, and reproducible synthesis profile make MT-2 a commonly referenced tool compound in peptide chemistry and receptor pharmacology research.*

Quality & Analytical Assurance

Each batch of MT-2 undergoes comprehensive analytical testing to confirm peptide identity, sequence accuracy, and purity. Verification through validated HPLC and mass spectrometry methodologies ensures consistency, reliability, and reproducibility for research applications.

Storage & Handling

MT-2 is supplied in lyophilized form to maintain stability during storage and shipping. Store unopened vials in a cool, dry environment protected from light. Reconstitution and handling should follow established laboratory best practices for peptide research to preserve molecular integrity and minimize degradation.

For further information on proper storage techniques, click the button…

Storage Instructions

Referenced Scientific Literature
Provided for informational and educational purposes only

  • Hadley ME, Haskell-Luevano C. The proopiomelanocortin system. Annals of the New York Academy of Sciences, 1999.
  • Hruby VJ, Lu D, Sharma SD, et al. Cyclic lactam α-melanotropin analogues of high potency. Journal of Medicinal Chemistry, 1995.
  • Wikberg JE, Mutulis F. Targeting melanocortin receptors: an approach to treat weight disorders and sexual dysfunction. Nature Reviews Drug Discovery, 2008.
  • Getting SJ. Melanocortin peptides and their receptors: new targets for anti-inflammatory therapy. Trends in Pharmacological Sciences, 2002.
  • Pritchard LE, Turnbull AV, White A. Pro-opiomelanocortin processing in the hypothalamus. Journal of Endocrinology, 2002.
  • Fan W, Boston BA, Kesterson RA, Hruby VJ, Cone RD. Role of melanocortinergic neurons in feeding and weight regulation. Nature, 1997.
  • Mountjoy KG. Functions for melanocortin receptors beyond pigmentation. Pigment Cell Research, 1994.
  • Schiöth HB, Chhajlani V, Muceniece R, Wikberg JE. Major pharmacological distinction of the ACTH receptor from other melanocortin receptors. Life Sciences, 1996.
  • Abdel-Malek ZA, Scott MC, Suzuki I, et al. The melanocortin system and human pigmentation. Pigment Cell Research, 2000.
  • Grieco P, Balse PM, Weinberg D, et al. Design and characterization of melanocortin peptides. Journal of Peptide Research, 2000.

ALL ARTICLES AND PRODUCT INFORMATION PROVIDED ON THIS WEBSITE ARE FOR INFORMATIONAL AND EDUCATIONAL PURPOSES ONLY. The products offered on this website are furnished for in-vitro studies only. In-vitro studies (Latin: in glass) are performed outside of the body. These products are not medicines or drugs and have not been approved by the FDA to prevent, treat or cure any medical condition, ailment or disease. Bodily introduction of any kind into humans or animals is strictly forbidden by law.