Product Usage: This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only.All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food or cosmetic.

BodyProtection157_5MG

BPC-157

BPC-157 is a synthetic pentadecapeptide derived from a partial sequence of Body Protection Compound (BPC), a peptide originally isolated from human gastric juice. In scientific research, BPC-157 is utilized as a peptide research tool for investigating peptide-mediated cellular signaling, tissue response mechanisms, and gastrointestinal–associated molecular pathways in controlled experimental models.*

Due to its short amino acid sequence and relative stability compared to larger endogenous peptides, BPC-157 has been widely referenced in preclinical research literature exploring cell–matrix interactions, angiogenic signaling pathways, and peptide effects on tissue integrity and cellular communication.*

  • Peptide Name: BPC-157
  • Peptide Class: Synthetic gastric pentadecapeptide (BPC fragment)
  • Amino Acid Length: 15 amino acids
  • Form: Lyophilized powder
  • Purity: ≥99% (HPLC verified)
  • Analytical Verification: HPLC and Mass Spectrometry (MS)
  • Manufacturing: Solid-phase peptide synthesis with in-house purification
  • Designation: For Research Use Only (RUO)
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Products will arrive in a lyophilized (powder) form for maximum stability.

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BPC-157

Scientific & Research Context

BPC-157 has been examined in published research for its involvement in cellular migration, angiogenic signaling, nitric oxide–related pathways, and extracellular matrix interactions across various experimental models.* Research literature has explored BPC-157 in the context of gastrointestinal integrity, musculoskeletal tissue signaling, vascular response mechanisms, and neurovascular communication.*

In laboratory research environments, BPC-157 has been utilized to investigate:*

  • Peptide-mediated signaling involved in tissue response and repair models*
  • Angiogenesis-related molecular pathways and endothelial signaling*
  • Cell migration, adhesion, and cytoskeletal organization*
  • Gastrointestinal-associated peptide signaling mechanisms*
  • Interactions between short-chain peptides and nitric oxide pathways*

Its defined sequence, reproducible synthesis, and extensive preclinical literature make BPC-157 a widely studied compound in peptide chemistry, molecular biology, and translational research settings.*

Quality & Analytical Assurance

Each batch of BPC-157 undergoes comprehensive analytical testing to confirm molecular identity, sequence accuracy, and purity. Verification using validated HPLC and MS methodologies ensures batch-to-batch consistency, reliability, and reproducibility for research applications.

Storage & Handling

BPC-157 is supplied in lyophilized form to enhance stability during storage and transport. Store unopened vials in a cool, dry environment protected from light. Reconstitution and handling should follow established peptide research and laboratory best practices to preserve molecular integrity and minimize degradation.

For further information on proper storage techniques, click the button…

Storage Instructions

Referenced Scientific Literature
Provided for informational and educational purposes only

  • Sikiric P., Rucman R., Turkovic B., et al. Stable gastric pentadecapeptide BPC 157: novel therapy in gastrointestinal and extraintestinal lesions. Curr. Pharm. Des. 2011;17(16):1612–1632.
  • Sikiric P., Seiwerth S., Rucman R., et al. Focus on BPC 157: a stable gastric pentadecapeptide with pleiotropic beneficial effects. Curr. Pharm. Des. 2014;20(7):1121–1136.
  • Sikiric P., Rucman R., Turkovic B., et al. Pentadecapeptide BPC 157 and the central nervous system. Neural Regen. Res. 2017;12(5):789–796.
  • Seiwerth S., Rucman R., Turkovic B., et al. BPC 157 and angiogenesis. Curr. Pharm. Des. 2018;24(18):1992–2001.
  • Sikiric P., Seiwerth S., Grabarevic Z., et al. The influence of pentadecapeptide BPC 157 on nitric oxide system. Life Sci. 2004;75(1):1–18.
  • Rucman R., Turkovic B., Sikiric P., et al. BPC 157 protects against muscle and tendon injuries in experimental models. J. Physiol. Pharmacol. 2012;63(5):597–607.
  • Staresinic M., Sebecic B., Patrlj L., et al. Gastric pentadecapeptide BPC 157 accelerates healing of transected rat Achilles tendon. J. Orthop. Res. 2003;21(6):976–983.
  • Krivic A., Anic T., Seiwerth S., et al. BPC 157 therapy improves muscle healing and counteracts corticosteroid impairment. J. Orthop. Res. 2006;24(9):1715–1723.
  • Hrelec M., Klicek R., Brcic L., et al. BPC 157 improves healing of gastrointestinal anastomoses in experimental models. Dig. Dis. Sci. 2009;54(4):816–827.
  • Sikiric P., Rucman R., Seiwerth S., et al. Brain–gut axis and BPC 157. Neuropharmacology 2016;110(Pt A):278–289.
  • Sikiric P., Rucman R., Turkovic B., et al. BPC 157 and vascular endothelium: interaction with NO pathways. Biomedicines 2020;8(6):190.
  • Gwyer D., Wragg N., Wilson S. BPC 157 and connective tissue healing: mechanistic insights from preclinical models. Regenerative Medicine 2019;14(5):437–449.
  • Huang T., et al. Body protective compound-157 enhances alkali-burn wound healing in vivo and promotes angiogenesis in vitro. Drug Des. Devel. Ther. 2015;9:2485–2499.
  • Drmic D., et al. Counteraction of perforated cecum lesions in rats: effects of pentadecapeptide BPC 157. World J. Gastroenterol. 2018;24(48):5462–5476.
  • Amic F., et al. Bypassing major venous occlusion and duodenal lesions in rats with BPC 157. World J. Gastroenterol. 2018;24(47):5366–5378.
  • Duzel A., et al. Stable gastric pentadecapeptide BPC 157 in colitis and ischemia–reperfusion injury. World J. Gastroenterol. 2017;23(48):8465–8488.
  • Vukojević J., et al. Inferior caval vein ligature and new insights with BPC 157. Vascul. Pharmacol. 2018;106:54–66.
  • Drmic D., et al. Celecoxib-induced gastrointestinal, liver and brain lesions counteracted by BPC 157. World J. Gastroenterol. 2017;23(29):5304–5312.
  • Hsieh M-J., et al. Therapeutic potential of pro-angiogenic BPC 157 associated with VEGFR2 activation. J. Mol. Med. 2017;95(3):323–333.
  • Grabarevic Z., et al. Influence of BPC 157 on nitric oxide agonist- and antagonist-induced lesions. J. Physiol. Paris 1997;91(3–5):139–149.
  • Sikiric P., et al. Novel cytoprotective mediator BPC 157: vascular recruitment and GI healing. Curr. Pharm. Des. 2018;24(18):1990–2001.
  • Seiwerth S., et al. BPC 157 and standard angiogenic growth factors. Curr. Pharm. Des. 2018;24(18):1972–1989.
  • Chang C-H., et al. Promoting effect of BPC 157 on tendon healing. J. Appl. Physiol. 2010;110(3):774–780.
  • Hu Y-L., et al. FAK and paxillin dynamics at focal adhesions. Sci. Rep. 2014;4:6024.
  • Škrlec K., et al. Engineering Lactococcus lactis as a delivery vehicle for BPC-157. Appl. Microbiol. Biotechnol. 2018;102(23):10103–10117.
  • Strinic D., et al. BPC 157 counteracts drug-induced QTc prolongation in rats. Life Sci. 2017;186:66–79.
  • Jelovac N., et al. BPC 157 attenuates neuroleptic-induced catalepsy and gastric ulcers. Eur. J. Pharmacol. 1999;379(1):19–31.
  • Tlak Gajger I., et al. Stable gastric pentadecapeptide BPC 157 in honeybee therapy. J. Vet. Pharmacol. Ther. 2018;41(4):614–621.

ALL ARTICLES AND PRODUCT INFORMATION PROVIDED ON THIS WEBSITE ARE FOR INFORMATIONAL AND EDUCATIONAL PURPOSES ONLY. The products offered on this website are furnished for in-vitro studies only. In-vitro studies (Latin: in glass) are performed outside of the body. These products are not medicines or drugs and have not been approved by the FDA to prevent, treat or cure any medical condition, ailment or disease. Bodily introduction of any kind into humans or animals is strictly forbidden by law.