Product Usage: This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only.All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food or cosmetic.

GH Releasing Peptide 2_10MG

GHRP-2

GHRP-2 (Growth Hormone–Releasing Peptide-2) is a synthetic hexapeptide belonging to the growth hormone secretagogue (GHS) class, developed for use as a research compound in studies involving growth hormone signaling and peptide–receptor interactions. In laboratory settings, GHRP-2 is utilized to investigate ghrelin receptor (GHS-R1a) activation and downstream endocrine signaling pathways under controlled experimental conditions.*

Originally characterized as a potent stimulator of growth hormone release in experimental models, GHRP-2 is widely referenced in endocrinology and molecular biology research for its well-defined mechanism of action and reproducible activity profile. Its compact structure and high receptor affinity make it a valuable tool for studying peptide-mediated signaling without the complexity of larger protein hormones.*

  • Peptide Name: GHRP-2
  • Peptide Class: Growth hormone–releasing peptide (GHS)
  • Amino Acid Length: 6 amino acids
  • Form: Lyophilized powder
  • Purity: ≥99% (HPLC verified)
  • Quantity: 10 mg per vial
  • Analytical Verification: HPLC and Mass Spectrometry (MS)
  • Manufacturing: Solid-phase peptide synthesis with in-house purification
  • Designation: For Research Use Only (RUO)

$60.00

$57.00 each
$54.00 each

Products will arrive in a lyophilized (powder) form for maximum stability.

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GHRP-2

Scientific & Research Context

In published scientific literature, GHRP-2 has been studied as a selective agonist of the growth hormone secretagogue receptor, independent of growth hormone–releasing hormone (GHRH) pathways.* Research models have used GHRP-2 to explore pulsatile growth hormone release, receptor desensitization, and interactions between ghrelin-mimetic peptides and endocrine feedback systems.*

Within experimental frameworks, GHRP-2 has been utilized to investigate:*

  • Growth hormone secretion dynamics and regulatory mechanisms*

  • Ghrelin receptor (GHS-R1a) signaling pathways*

  • Peptide–receptor binding affinity and structure–activity relationships*

  • Interactions between growth hormone secretagogues and hypothalamic signaling*

  • Comparative analysis of synthetic GHS compounds in vitro*

Due to its potency and short amino acid sequence, GHRP-2 is frequently selected for mechanistic studies requiring precise temporal control and repeatable receptor activation.*

Quality & Analytical Assurance

Each batch of GHRP-2 is produced using validated solid-phase peptide synthesis techniques and undergoes comprehensive analytical testing to confirm molecular identity, sequence accuracy, and purity. Verification by high-performance liquid chromatography (HPLC) and mass spectrometry (MS) ensures consistency, reliability, and reproducibility for research applications.

Storage & Handling

GHRP-2 is supplied as a lyophilized powder to maintain stability during storage and transport. Store unopened vials in a cool, dry environment protected from light. Reconstitution and handling should follow standard laboratory peptide protocols to preserve molecular integrity and minimize degradation.

For further information on proper storage techniques, click the button…

Storage Instructions

Referenced Scientific Literature
Provided for informational and educational purposes only

  • Hu, R. et al. Effects of GHRP-2 and cysteamine administration on growth performance, somatotropic axis hormone and muscle protein deposition in yaks (Bos grunniens) with growth retardation. PLoS One, 2016.
  • Yamamoto, D. et al. GHRP-2 directly acts on myocytes to attenuate dexamethasone-induced expression of Atrogin-1 and MuRF1. Life Sciences, 2008.
  • Phung, L. T. et al. Effects of growth hormone-releasing peptide-2 on growth hormone release and growth performance in swine. Domestic Animal Endocrinology, 2000.
  • Laferrère, B. et al. Growth hormone-releasing peptide-2, like ghrelin, increases food intake in healthy men. Journal of Clinical Endocrinology & Metabolism, 2005.
  • Laferrère, B. et al. Obese subjects respond to the stimulatory effect of the ghrelin agonist GHRP-2 on food intake. Obesity, 2006.
  • Muccioli, G. et al. Growth hormone-releasing peptides and the cardiovascular system. Annales d’Endocrinologie, 2000.
  • Bodart, V. et al. Identification and characterization of a growth hormone-releasing peptide receptor in the heart. Circulation Research, 1999.
  • Taub, D. D. et al. Rejuvenation of the aging thymus: growth hormone- and ghrelin-mediated signaling pathways. Current Opinion in Pharmacology, 2010.
  • Copinschi, G. et al. Prolonged oral treatment with MK-677 improves sleep quality in humans. Neuroendocrinology, 1997.
  • Zeng, P. et al. GHRP-2 produces antinociceptive effects via opioid receptors at the supraspinal level. Peptides, 2014.
  • Moulin, A. et al. Recent developments in ghrelin receptor ligands. ChemMedChem, 2007.
  • Bowers, C. Y. et al. Growth hormone-releasing peptide activity and pituitary specificity. Endocrinology, 1990.
  • Jacks, T. et al. Growth hormone secretagogue activity in animal models. Endocrinology, 1994.
  • Smith, R. G. et al. Identification of a non-peptidyl growth hormone secretagogue. Science, 1997.
  • Howard, A. D. et al. A receptor in pituitary and hypothalamus that functions in growth hormone release. Science, 1996.
  • Ghigo, E. et al. Growth hormone-releasing activity of hexarelin and GHRP-2 in humans. Journal of Clinical Endocrinology & Metabolism, 1996.
  • Korbonits, M. et al. The growth hormone secretagogue receptor. Journal of Endocrinology, 1998.
  • Muccioli, G. et al. Growth hormone secretagogues and the central nervous system. Endocrine, 2000.
  • Kojima, M. et al. Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature, 1999.
  • Müller, T. D. et al. Ghrelin and growth hormone secretagogue biology. Molecular Metabolism, 2015.

ALL ARTICLES AND PRODUCT INFORMATION PROVIDED ON THIS WEBSITE ARE FOR INFORMATIONAL AND EDUCATIONAL PURPOSES ONLY. The products offered on this website are furnished for in-vitro studies only. In-vitro studies (Latin: in glass) are performed outside of the body. These products are not medicines or drugs and have not been approved by the FDA to prevent, treat or cure any medical condition, ailment or disease. Bodily introduction of any kind into humans or animals is strictly forbidden by law.